2-[ (4-Amino-3-methylphenyl) Ethylamino]Ethyl Sulfate CD-3 25646-71-3 China Chemical Intermediate

• CAS No.: 25646-71-3
• Formula: C12h23n3o6s2
• EINECS: 247-161-5
• Model NO.: JT22PHA
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Good Chemical Product
• Colour: White
• Name: 2-[(4-Amino-3-Methylphenyl)Ethylamino]Ethyl Sulfat
• Formula Weight: 369.45
• Color: White
• Assay: 99%
• Delivery: by Sea, by Air, by Land/EMS/TNT/DHL/UPS/FedEx
• Application: an Important Raw Material
• Storage Temp: Room Temperature and Avoid Light
• Standard: Good Chemical Product
• Transport Package: 25kg/Bag, Customization
• Specification: 25kg,50kg,180kg,200kg,250kg,1000kg,customization
• Trademark: Hubei Jiutian
• Origin: Wuhan
• HS Code: 29339900
• Production Capacity: 15mt/Month

Product Description

2-[(4-Amino-3-methylphenyl)ethylamino]ethyl sulfate Basic information
 

This product is used as a color developer for Eastman color-negative film and Ektachrome reversal film; color developer for use in color microautoradiography; for color development of immunogold-Iabeled antibodies.Pitavastatin, launched for the treatment of hypercholesterolemia, belongs to the family of second-generation statins, also referred to as superstatins due to their improved efficacy as cholesterol lowering agents. Like other statins, pitavastatin reduces plasma cholesterol levels by competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme of cholesterol biosynthesis in the liver. It is a more potent inhibitor of HMG-CoA reductase than the previously marketed statins and has the potential benefit of not undergoing significant metabolism by CYP3A4. Pitavastatin is synthesized in a multi-step sequence, including the key step of introducing the dihydroxyheptenoate side chain by cross-coupling of a 3-iodoquinoline intermediate with an alkenylborane reagent. Unlike rosuvastatin, pitavastatin has a high oral bioavailability (~80%). Plasma protein binding is also high for pitavastatin (>95%), and regardless of the dosing, the highest tissue levels are found in the liver, its target organ. After oral administration, the peak plasma concentration is reached at ,0.8 h and the mean elimination half-life is ~11 h. Pitavastatin is only minimally metabolized, mainly by CYP2C8 and CYP2C9, and the predominant route of elimination of the parent drug and its metabolites is by means of bile excretion followed by elimination in the feces. In clinical studies, oral doses of 2-4 mg/day of pitavastatin produced dose-dependent reduction in LDL-cholesterol levels by 40-48% from baseline in patients with heterozygous familial hypercholesterolemia. In a 12-week double-blind comparative study, pitavastatin (2 mg/day) was more effective than pravastatin (10 mg/day) in reducing LDL-cholesterol levels (38 and 18%, respectively); however, both agents produced similar increases in HDL-cholesterol (~9%). The drug was well tolerated and the adverse reactions were mild and transient.
A competitive inhibitor of HMG-CoA reductase.
Pitavastatin calcium (Livalo) is a novel member of the medication class of statins
A competitive inhibitor of HMG-CoA reductase. Antilipemic.
product details

Item	parameter
Name	2-[(4-Amino-3-methylphenyl)ethylamino]ethyl sulfate
Synonyms	N-(2-(4-amino-N-ethyl-m-toluidino)ethyl)methanesulphonamide sesquisulphate
CAS	25646-71-3
Molecular Formula	C12H23N3O6S2
Formula Weight	369.45
Appearance	White powder
Melting Point	----
Boiling point	----
Assay	99%
Water	<0.5%
Residue on ignition	<0.5%
Stability	Stable
Storage Temp	room temperature and avoid light
Origin	Wuhan China
Application	color developer for Eastman color-negative film
Delivery	by sea,by air,by Land/EMS/TNT/DHL/UPS/FedEx

Packing                                                                                                                                     

Liquid products

• 25kg,50kg,180kg,200kg,250kg,1000kg,as your needs

Solid products

• 25kg,50kg,as your needs

Shipping                                                                                                                                    

Logistics transportation methods can be divided into various ways according to the different transportation means.

• Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
• For mass orders, it will be delivered by air or sea.
• Depending on your location, please allow 1-5 business days for your order to arrive.
• For small order, please expect 3-7 days by UPS DHL EMS.
• For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

 

Our service                                                                                                                               

• We have our own research and development team, laboratory, pilot workshop and production plant.
• Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
• Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
• The customer comes first, we provide reasonable price, high quality product and prompt shipment.
• We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
• Quick and clear response to customers questions.Warm after sale service, we will help to solve the problems in your usage.
• We could make our price discount if you place a substantial order with us.

Our Advantages                                                                                                                      

• Your inquiry related to our products or prices will be replied in 24 hours.
• We have our own research and development team, laboratory, pilot workshop and production plant.
• Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
• Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
• Protection of your sales area, ideas of design and all your private information.
• Best quality and competitive price.

Frequently Asked Question                                                                                                      

• Q1: Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by customers.

• Q2: How to start orders or make payments?
A : PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union LC,Moneygram or Paypal.

• Q3: What's your MOQ?
A : Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that 
sample charge is 100% paid.
• Q4: How about delivery leadtime?
A : Delivery lead time: About 3-5 days after payment confirmed.(Chinese holiday not

included)

• Q5: Is there a discount?
A : Different quantity has different discount.

• Q6: How to contact us ?
A : You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.

• Q7: How to confirm the Product Quality before placing orders?
A : You can get free samples for some products,you only need to pay the shipping cost or 
arrange a courier to us and take the samples. You can send us your product specifications 
and requests,we will manufacture the products according to your requests.

Our R&D laboratory                                                           Our Factory                                        

Detecting chamber
Quality
We strictly emphasize that products we provide will satisfy or exceed the quality standard of customer.This is to guarantee deliveries of safe and high quality products with reliable services.
We promote the philosophy of treating everyone with objectivity and respect.We will honor our commitments with our customers,suppliers,and respect.We through unbiased pricing,products,and honesty.
Factories and workshops
We is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in Pharmaceuticals Raw Material, Pesticides Raw Materials, API Raw Material, OLED Intermediates, UV Absorber Additive, Chemical Food Additives, Plant Extract Powder, Chinese Herbal Medicine, Polyimide Monomer, Impurity Reference Standards research and development, production, sales and operation or agency of various products and technology import and export business.