Curcumin Basic information
Curcumin, Natural Yellow 3, Diferuloylmethane;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(e,e)-6-heptadiene-3;5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-6-heptadiene-3;6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-1;curcuma;haidr;halad;haldar
Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, and antitumor activities. It inhibits nitric oxide (NO) production (IC50 = 6 μM) and reduces inducible nitric oxide synthase (iNOS) activity in LPS-stimulated RAW 264.7 cells.Curcumin inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells. In vivo, curcumin decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis. Curcumin (100 or 200 mg/kg) prevents ovalbumin-induced accumulation of 3-nitrotyrosine (3-NT), a marker of oxidative stress, in mouse heart. Topical administration of curcumin (1-10 μmol) reduces the number of tumors induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mouse skin. Dietary administration of curcumin reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in rats.
The main source of curcumin is the root of Zingiberaceae Curcuma aromatica, rhizome of Curcuma longa (Jiang Huang), Curcuma zedoaria, and Acorus calamus. Among them, Jiang Huang contains about 3-6% curcumin. The traditional Chinese medicine, Jiang Huang, is the root tuber of perennial herbaceous plant Curcuma longa L. of family Zingiberaceae. It was firstly recorded in the "Tang materia medica" (Xin Xiu Ben Cao). It is pungent, bitter, and warm and enters the liver and spleen meridians. It activates the blood, moves qi, dredges meridians, and alleviates pain. In India and other Asian countries, Jiang Huang has more than 6000?years of application history. In Japan, Jiang Huang has a long history of health care, and the people of Okinawa Island regarded Jiang Huang as a holy tribute to the emperor. Jiang Huang mainly comes from Taiwan, Fujian, Guangdong, Guangxi, Yunnan, and Tibet of China and other regions in East Asia and Southeast Asia. It grows in warm and humid climate and sunny environment with abundant rainfall and fears cold frost, drought, and flood. At present, Chinese Pharmacopoeia only included Jiang Huang and Yu Jin which contains curcumin, while curcumin is not included.
For preparing curcuma paper, pH range 8-9. In the detection of boron.
A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
antiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal, lipo/cyclooxygenase inhibitor
Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). The curcuminoids are polyphenols and are responsible for the yellow color of turmeric.
| Item |
parameter |
| Name |
Curcumin |
| Synonyms |
curcuma |
| CAS |
458-37-7 |
| Molecular Formula |
C21H20O6 |
| Formula Weight |
368.38 |
| Appearance |
Yellow Powder |
| Melting Point |
183 °C |
| Boiling point |
418.73°C (rough estimate) |
| Assay |
99% |
| Water |
<0.5% |
| Residue on ignition |
<0.5% |
| Stability |
Stable |
| Storage Temp |
room temperature and avoid light |
| Origin |
Wuhan China |
| Application |
Heterocyclic Compounds;Intermediates |
| Delivery |
by land,EMS,TNT,DHL,UPS,FEDEX |
Packing
Liquid products
- 25kg,50kg,180kg,200kg,250kg,1000kg,as your needs
Solid products
Shipping
Logistics transportation methods can be divided into various ways according to the different transportation means.
• Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
• For mass orders, it will be delivered by air or sea.
• Depending on your location, please allow 1-5 business days for your order to arrive.
• For small order, please expect 3-7 days by UPS DHL EMS.
• For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
Our service
- We have our own research and development team, laboratory, pilot workshop and production plant.
- Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
- Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
- The customer comes first, we provide reasonable price, high quality product and prompt shipment.
- We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
- Quick and clear response to customers questions.Warm after sale service, we will help to solve the problems in your usage.
- We could make our price discount if you place a substantial order with us.
Our Advantages
- Your inquiry related to our products or prices will be replied in 24 hours.
- We have our own research and development team, laboratory, pilot workshop and production plant.
- Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
- Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
- Protection of your sales area, ideas of design and all your private information.
- Best quality and competitive price.
Frequently Asked Question
• Q1: Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by customers.
• Q2: How to start orders or make payments?
A : PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union LC,Moneygram or Paypal.
• Q3: What's your MOQ?
A : Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that
sample charge is 100% paid.
• Q4: How about delivery leadtime?
A : Delivery lead time: About 3-5 days after payment confirmed.(Chinese holiday not
included)
• Q5: Is there a discount?
A : Different quantity has different discount.
• Q6: How to contact us ?
A : You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.
• Q7: How to confirm the Product Quality before placing orders?
A : You can get free samples for some products,you only need to pay the shipping cost or
arrange a courier to us and take the samples. You can send us your product specifications
and requests,we will manufacture the products according to your requests.
Our R&D laboratory Our Factory
Detecting chamber
Quality
We strictly emphasize that products we provide will satisfy or exceed the quality standard of customer.This is to guarantee deliveries of safe and high quality products with reliable services.
We promote the philosophy of treating everyone with objectivity and respect.We will honor our commitments with our customers,suppliers,and respect.We through unbiased pricing,products,and honesty.
Factories and workshops
We is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in Pharmaceuticals Raw Material, Pesticides Raw Materials, API Raw Material, OLED Intermediates, UV Absorber Additive, Chemical Food Additives, Plant Extract Powder, Chinese Herbal Medicine, Polyimide Monomer, Impurity Reference Standards research and development, production, sales and operation or agency of various products and technology import and export business.
Audited Supplier 
Audited Supplier 
){kind=link}
){kind=link}