Lithium chloride Basic information
Lithium chloride is useful for the production of lithiu m metal, and for the generation of Mn(0) species which can be used in free radical cyclizations. It can serve as a flame colorant to generate dark red flames, a brazing flux for aluminum in automobiles, a hygrometer, and a desiccant for drying air streams. On exposure to air, it becomes a solution with the concentration directly related to relative humidity of the atmosphere, and hence serves as a relative humidity standard in calibrating hygrometers. Apart from being a source of chloride, it serves as an additive in the Stille reaction in organic synthesis, and to precipitate RNA from cellular extracts. Being biologically significant, it finds applications in a wide variety of assays to study cell-fate and neurobiology. Lithium chloride has been found to inhibit virus infection. Lithium chloride is used as an antidepressant, especially in the treatment of manic depression and bipolar disorders. Lithium chloride solutions are used in large dehumidification systems in the air-conditioning industry. This use depends on the low equilibrium pressure of water vapor above solutions of lithium chloride. After the solutions have absorbed water, they are regenerated by heating.
Lithium chloride is used in a number of salt mixtures. Such salt mixtures have low melting points allowing the material to be used in brazing fluxes and brazing baths. The molten lithium chloride-potassium chloride eutectic mixture can be used as an electrolyte. The mixture is electrolyzed for the production of lithi um metal and is used as an electrolyte in voltaic cells.
manufacture of mineral waters; in pyrotechnics; soldering aluminum; in refrigerating machines.
Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company Pfizer for treating rheumatoid arthritis, trade name Xeljanz, for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid arthritis (RA) in adult patients. This product is a Janus kinase inhibitor, administered twice daily.
November 6, 2012, the US Food and Drug Administration (FDA) and Pfizer jointly announced Tofacitinib citrate is approved for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid joints arthritis (RA) in adult patients.
Xeljanz can be used as monotherapy or in combination with methotrexate or other non-biological disease-modifying antirheumatic drugs (the DMARD) in combination. This medicine should not be in combination with biological DMARD or strong immunosuppressants (such as cyclosporine and azathioprine). Xeljanz is approved by the daily dose of 2 times, each time 5mg.
Seven clinical trials evaluated the safety and efficacy of Tofacitinib citrate in moderate to severe active RA in adult patients. In all tests, compared with patients receiving placebo, patients receiving Xeljanz treatment showed significant improvement in clinical response and physical function.
In Clinical trials, the most common adverse events were upper respiratory tract infection, headache, diarrhea, nasal congestion, sore throat, and nasopharyngitis.
Using Xeljanz was associated with an increased risk of serious infections, including opportunistic infections, tuberculosis, cancer and lymphoma. Xeljanz product label attaches boxed warning on these security risks. Xeljanz treatment is also associated with reducing blood cell counts and increasing cholesterol and liver enzyme values.
In order to study Xeljanz long-term impact on heart disease, cancer and severe infections, FDA requires for a post-marketing study, which will evaluate two doses of Xeljanz (Tofacitinib citrate) therapy, and accept a integration of another group of patients approved by the treatment as a control.
Tofacitinib citrate has been used:
- as a ligand for human serum albumin in fluorescence quenching, dynamic light scattering (DLS) measurements, differential scanning calorimetry and molecular docking studies
- as a medium supplement for full depth articular cartilage (FDC) explants to monitor cytokine-induced proteoglycan loss
- as a Janus kinase inhibitor in MCF7 breast cancer cells
product details
| Item |
parameter |
| Name |
Lithium chloride |
| Synonyms |
LITHIUMCHLORIDE,POWDER,REAGENT,ACS |
| CAS |
7447-41-8 |
| Molecular Formula |
LiCl |
| Formula Weight |
42.39 |
| Appearance |
White powder |
| Melting Point |
605 °C (lit.) |
| Boiling point |
1383 °C/1 atm (lit.) |
| Assay |
99% |
| Water |
<0.5% |
| Residue on ignition |
<0.5% |
| Stability |
Stable |
| Storage Temp |
room temperature and avoid light |
| Origin |
Wuhan China |
| Application |
antidepressant, especially in the treatment of manic depression and bipolar disorders |
| Delivery |
by sea,by air,by Land/EMS/TNT/DHL/UPS/FedEx |
Packing
Liquid products
- 25kg,50kg,180kg,200kg,250kg,1000kg,as your needs
Solid products
Shipping
Logistics transportation methods can be divided into various ways according to the different transportation means.
• Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
• For mass orders, it will be delivered by air or sea.
• Depending on your location, please allow 1-5 business days for your order to arrive.
• For small order, please expect 3-7 days by UPS DHL EMS.
• For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
Our service
- We have our own research and development team, laboratory, pilot workshop and production plant.
- Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
- Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
- The customer comes first, we provide reasonable price, high quality product and prompt shipment.
- We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
- Quick and clear response to customers questions.Warm after sale service, we will help to solve the problems in your usage.
- We could make our price discount if you place a substantial order with us.
Our Advantages
- Your inquiry related to our products or prices will be replied in 24 hours.
- We have our own research and development team, laboratory, pilot workshop and production plant.
- Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
- Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
- Protection of your sales area, ideas of design and all your private information.
- Best quality and competitive price.
Frequently Asked Question
• Q1: Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by customers.
• Q2: How to start orders or make payments?
A : PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union LC,Moneygram or Paypal.
• Q3: What's your MOQ?
A : Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that
sample charge is 100% paid.
• Q4: How about delivery leadtime?
A : Delivery lead time: About 3-5 days after payment confirmed.(Chinese holiday not
included)
• Q5: Is there a discount?
A : Different quantity has different discount.
• Q6: How to contact us ?
A : You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.
• Q7: How to confirm the Product Quality before placing orders?
A : You can get free samples for some products,you only need to pay the shipping cost or
arrange a courier to us and take the samples. You can send us your product specifications
and requests,we will manufacture the products according to your requests.
Our R&D laboratory Our Factory
Detecting chamber
Quality
We strictly emphasize that products we provide will satisfy or exceed the quality standard of customer.This is to guarantee deliveries of safe and high quality products with reliable services.
We promote the philosophy of treating everyone with objectivity and respect.We will honor our commitments with our customers,suppliers,and respect.We through unbiased pricing,products,and honesty.
Factories and workshops
We is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in Pharmaceuticals Raw Material, Pesticides Raw Materials, API Raw Material, OLED Intermediates, UV Absorber Additive, Chemical Food Additives, Plant Extract Powder, Chinese Herbal Medicine, Polyimide Monomer, Impurity Reference Standards research and development, production, sales and operation or agency of various products and technology import and export business.
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Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company Pfizer for treating rheumatoid arthritis, trade name Xeljanz, for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid arthritis (RA) in adult patients. This product is a Janus kinase inhibitor, administered twice daily.
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