β-Nicotinamide adenine dinucleotide information
OSTEOPONTIN, GST FUSION;)-1-beta-d-ribofuranosylpyridiniumhydroxide,innersalt;adenine-nicotinamidedinucleotide;adenosine5'-(trihydrogendiphosphate),p'.fwdarw.'-esterwith3-(aminocarbonyl;Adenosine5'-(trihydrogendiphosphate),P'.fwdarw.5'-esterwith3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium,innersalt;beta-diphosphopyridine;cozymasei;enzopride
β-Nicotinamide adenine dinucleotide (NAD+) plays a major role in metabolism as a cofactor and mobile electron acceptor. NAD+ is a required oxidizing cosubstrate for many enzymes. It is reduced to NADH (Cat# N-035) which carries electrons to the electron transport chain for subsequent oxidative phorphorylation and ATP production. NAD+ is capable of donating ADP-ribose moieties to a protein, producing nicotinamide in the process. Sirtuin enzymes use NAD+ as a substrate to deacetylate proteins and direct activity between the nucleus and mitochondria. NAD+ is regenerated by fermentation and by oxidative phosphorylation.
NAD+, known more formally as nicotinamide adenine dinucleotide, is a signaling molecule as well as a cofactor or substrate for many enzymes. It acts as an oxidizing agent, accepting electrons from other molecules while being converted to its reduced form, NADH (Item No. 16078). NAD+ is also essential for the activity of several enzymes, including poly(ADP)-ribose polymerases and cADP-ribose synthases. For example, it is used by some sirtuins to mediate protein deacetylation, producing O-acetyl-ADP-ribose and nicotinamide as well as the deacetylated protein.
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β-Nicotinamide Adenine Dinucleotide is a coeznyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate group. β-Nicotinamide Adenine Dinucleotide acts as a c oenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleot ide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
β-Nicotinamide adenine dinucleotide (β-NAD) has been used for the preparation of deacetylated tubulin. It has also been used for UDP-glucose-6-hydrogenase (UGDH) enzyme activity assay of orital fibroblast cell lysates.
β-Nicotinamide adenine dinucleotide (β-NAD) is a neuromodulator and an inhibitory neurotransmitter. It is an agonist for purinergic (P2Y1) receptors.
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
| Item |
parameter |
| Name |
β-Nicotinamide adenine dinucleotide |
| Synonyms |
cozymasei |
| CAS |
53-84-9 |
| Molecular Formula |
C21H27N7O14P2 |
| Formula Weight |
663.43 |
| Appearance |
white powder |
| Melting Point |
140-142 °C (decomp) |
| Boiling point |
--- |
| Assay |
99% |
| Water |
<0.5% |
| Residue on ignition |
<0.5% |
| Stability |
Stable |
| Storage Temp |
room temperature and avoid light |
| Origin |
Wuhan China |
| Application |
Raw materials for food |
| Delivery |
by land/EMS/TNT/DHL/UPS/FEDEX |
Packing
Liquid products
- 25kg,50kg,180kg,200kg,250kg,1000kg,as your needs
Solid products
Shipping
Logistics transportation methods can be divided into various ways according to the different transportation means.
• Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
• For mass orders, it will be delivered by air or sea.
• Depending on your location, please allow 1-5 business days for your order to arrive.
• For small order, please expect 3-7 days by UPS DHL EMS.
• For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
Our service
- We have our own research and development team, laboratory, pilot workshop and production plant.
- Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
- Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
- The customer comes first, we provide reasonable price, high quality product and prompt shipment.
- We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
- Quick and clear response to customers questions.Warm after sale service, we will help to solve the problems in your usage.
- We could make our price discount if you place a substantial order with us.
Our Advantages
- Your inquiry related to our products or prices will be replied in 24 hours.
- We have our own research and development team, laboratory, pilot workshop and production plant.
- Factory production has the most stable and the best production processes, to ensure that you are given the best prices and the highest quality products.
- Not only do we provide our customers with products, but we also provide them with free product usage methods and subsequent technical guidance
- Protection of your sales area, ideas of design and all your private information.
- Best quality and competitive price.
Frequently Asked Question
• Q1: Can I get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by customers.
• Q2: How to start orders or make payments?
A : PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union LC,Moneygram or Paypal.
• Q3: What's your MOQ?
A : Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that
sample charge is 100% paid.
• Q4: How about delivery leadtime?
A : Delivery lead time: About 3-5 days after payment confirmed.(Chinese holiday not
included)
• Q5: Is there a discount?
A : Different quantity has different discount.
• Q6: How to contact us ?
A : You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.
• Q7: How to confirm the Product Quality before placing orders?
A : You can get free samples for some products,you only need to pay the shipping cost or
arrange a courier to us and take the samples. You can send us your product specifications
and requests,we will manufacture the products according to your requests.
Our R&D laboratory Our Factory
Detecting chamber
Quality
We strictly emphasize that products we provide will satisfy or exceed the quality standard of customer.This is to guarantee deliveries of safe and high quality products with reliable services.
We promote the philosophy of treating everyone with objectivity and respect.We will honor our commitments with our customers,suppliers,and respect.We through unbiased pricing,products,and honesty.
Factories and workshops
We is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in Pharmaceuticals Raw Material, Pesticides Raw Materials, API Raw Material, OLED Intermediates, UV Absorber Additive, Chemical Food Additives, Plant Extract Powder, Chinese Herbal Medicine, Polyimide Monomer, Impurity Reference Standards research and development, production, sales and operation or agency of various products and technology import and export business.
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